At the turn of the sixteenth century, Michelangelo (Mark Frankel),Raphael (Andrea Prodan),and Leonardo Da Vinci (John Glover) create their masterpieces, while dealing with religious persecution, political turmoil, and the discovery of America.

• Turner Pictures (I)
• RAI
• F. Murray Abraham
• Mark Frankel
• Vittorio Amandola
• Steven Berkoff
• Pier Paolo Capponi
• Alessandro Gassmann
• Ian Holm
• Ornella Muti